Transcription factors involved in terpenoid indole alkaloid biosynthesis in Catharanthus roseus
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چکیده
منابع مشابه
The transcription factor CrWRKY1 positively regulates the terpenoid indole alkaloid biosynthesis in Catharanthus roseus.
Catharanthus roseus produces a large array of terpenoid indole alkaloids (TIAs) that are an important source of natural or semisynthetic anticancer drugs. The biosynthesis of TIAs is tissue specific and induced by certain phytohormones and fungal elicitors, indicating the involvement of a complex transcriptional control network. However, the transcriptional regulation of the TIA pathway is poor...
متن کاملGene-to-metabolite networks for terpenoid indole alkaloid biosynthesis in Catharanthus roseus cells.
Rational engineering of complicated metabolic networks involved in the production of biologically active plant compounds has been greatly impeded by our poor understanding of the regulatory and metabolic pathways underlying the biosynthesis of these compounds. Whereas comprehensive genome-wide functional genomics approaches can be successfully applied to analyze a select number of model plants,...
متن کاملSubcellular Localization of Enzymes Involved in Indole Alkaloid Biosynthesis in Catharanthus roseus.
The subcellular localization of enzymes involved in indole alkaloid biosynthesis in leaves of Catharanthus roseus has been investigated. Tryptophan decarboxylase and strictosidine synthase which together produce strictosidine, the first indole alkaloid of this pathway, are both cytoplasmic enzymes. S-Adenosyl-l-methionine: 16-methoxy-2,3-dihydro-3-hydroxytabersonine-N-methyltransferase which ca...
متن کاملDissertation Metabolic Engineering and Elucidation of the Terpenoid Indole Alkaloid Pathway in Catharanthus Roseus
................................................................................................................................................. ii ACKNOWLEDGEMENTS .......................................................................................................................... v 1. CHAPTER 1 CONCLUSIONS ....................................................................................
متن کاملTranscriptome analysis in Catharanthus roseus leaves and roots for comparative terpenoid indole alkaloid profiles.
In Catharanthus roseus (L.) G. Don each tissue is known to produce a distinct spectrum of terpenoid indole alkaloids. Since the invaluable antineoplastic bisindole alkaloids are restricted to the aerial parts of the plant and do not occur in its underground tissues, identification of the structural and regulatory factors operating distinctly in the shoot/leaf of the plant will be a necessity fo...
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ژورنال
عنوان ژورنال: Phytochemistry Reviews
سال: 2007
ISSN: 1568-7767,1572-980X
DOI: 10.1007/s11101-006-9051-z